As per Wikipedia-

Denuvo Anti-Tamper , or Denuvo, is an anti-tamper technology developed by the Austrian company Denuvo Software Solutions GmbH. Denuvo Anti-Tamper technology continuously encrypts and decrypts itself so that it is impossible to crack. Denuvo Software Solutions has stated that the technology "does not continuously encrypt and decrypt any data on storage media. To do so would be of no benefit in terms of security or performance." The company has not revealed how Denuvo Anti-Tamper works.

2016's games that use Denuvo Anti Tamper technology are -

• Rise of the Tomb Raider
• Unravel
• Far Cry Primal
• Plants vs. Zombies: Garden Warfare 2
• Hitman
• Need for Speed
• ADR1FT
• DOOM
• Total War: Warhammer
• Mirror's Edge Catalyst
• Deus Ex: Mankind Divided
• The Division
• Friday the 13th: The Game
• Mass Effect: Andromeda
• Star Citizen
• No Man's Sky
• Overwatch
• Fifa 17
• Battlefield 5
• Dishonored 2
• Dead Island 2
• Sniper: Ghost Warrior 3